Bộ tổng hợp peptide tự động quy mô sản xuất

Thông số kỹ thuật:

General:

• Easy to Use Fully Automated Peptide/Organic Synthesizer at the Lowest Operating Cost

• Simultaneous and Parallel Syntheses of Two (Standard Option) to Six Different Peptides (Optional) Under Inert Conditions

• Isolated TFA or Piperidine Lines as integrated deprotection/cleavage system

• Flexible design for conducting ANY Type of Solid Phase Organic Synthesis including Fmoc- or BOC-Chemistries.

• Specially designed for the Synthesis of long chain and/or difficult peptides:

  • Use of In-Situ and/or Pre-activation Protocols

  • Optional Heating/cooling/Microwave (upon request)

  • Optional UV-monitoring of the reactions progress (upon request)

• Online Automated Cleavage Reactions (Excludes HF-cleavage reactions)

• Innovative Bench Top Design with a small foot print

• Fully Enclosed System, No hood is required

• Emergency Stop /Pause Feature at any time during the Synthesis

• On-Lines Technical Support

• One Year Full Warranty on parts and labor.  Additional annual service contracts available upon request

• Power Supply: 110-220v/50-60Hz depending on the area of usage

 Amino Acid Vessels:

• Multiple Deliveries from 24x90mL Amino Acid/Reagent Vessels (Standard Option)

• Direct dissolving and pre-activation of amino acid powders by the instrument

• Pre-activation and deliveries under inert conditions

• Optional 250mL and 500mL (or even larger) Amino Acid Vessels for Large Scale Syntheses (The Focus XCi model)

• Use of pre-dissolved solutions of monomers, if required

• Can be used as Cleavage Vessels, Reagent Bottles as well as Solution Phase Reactors for the synthesis of any desired intermediate of final compounds

 Reaction Vessels:

• Average Scales in 25-100mL Reactors: 0.01-5.0mmol per Reactor (Total 30mmol in 6RV model based 0.5mmol/g resin loading)

• Ultimate Scale in 300mL Reactors: 15mmol per Reactor (Total 45mmol in 4-6RV model based 0.5mmol/g resin loading)

• Easily interchangeable Reactors for multiple scale-up purposes.

• Available Reactor Volumes: 25mL; 50mL, 100mL, 200mL, 300mL

• Special Reactor system for larger scales (0.5-2L) maybe designed upon request (The Focus XCi model).

• Solvent Delivery from the Top as well as Bottom of the Reactor under inert conditions

• Fast Emptying of the Reaction Vessels by a positive pressure of an inert gas regulated at 10psi

• Shower Head Technology For Fast and Cost Effective Washing of Resin and the entire reactors

• Three Agitation modes at adjustable rates: Vortex Shaking, Nitrogen/Argon bubbling or the both

• Optional Heating / Cooling / Microwave Systems upon request

 Reagent/Solvent Vessels:

• 6-8 Flexible lines with interchangeable 0.5-20L containers for the Reagents and Solvents Deliveries

• Standard Option: 2x5L; 2x2L; 2x1L containers

 Measuring Vessel:

• Interchangeable measuring vessels at different working volumes in 15-90mL (Optional larger or smaller measuring vessels available at extra charge)

• Accurate calibration of all the liquid deliveries using Pressure/Time Calibration or photocell technology

• Accurate measurements of liquids prior to deliveries

• Pre-activation of amino acids (optional)

 Software System:

• Versatile Software installed on a desk top PC included with LCD-monitor, keyboard, mouse pad and a printer (Optional Laptop available upon request)

• Unique and flexible capabilities developed by Chemists for Novice and Expert Chemists

• User friendly Software for easy to prepare and easy to use

• Fully Automated Optimized Standard Protocols for Fmoc- or BOC Peptide Chemistry

• Flexible Custom Designable Protocols for ANY type of Solid Phase Organic Syntheses (PND, DNA, Oligopeptides, Carbohydrate Synthesis, etc)

• Synthesis of Long Chain and/or Difficult Peptides at the shortest possible time: Pre-activation or In-Situ activation of the Amino Acids per need; Single or Multiple Couplings per need