General:
Easy to Use Fully Automated Peptide/Organic Synthesizer at the Lowest Operating Cost
Simultaneous and Parallel Syntheses of Two (Standard Option) to Six Different Peptides (Optional) Under Inert Conditions
Isolated TFA or Piperidine Lines as integrated deprotection/cleavage system
Flexible design for conducting ANY Type of Solid Phase Organic Synthesis including Fmoc- or BOC-Chemistries.
Specially designed for the Synthesis of long chain and/or difficult peptides:
Use of In-Situ and/or Pre-activation Protocols
Optional Heating/cooling/Microwave (upon request)
Optional UV-monitoring of the reactions progress (upon request)
Online Automated Cleavage Reactions (Excludes HF-cleavage reactions)
Innovative Bench Top Design with a small foot print
Fully Enclosed System, No hood is required
Emergency Stop /Pause Feature at any time during the Synthesis
On-Lines Technical Support
One Year Full Warranty on parts and labor. Additional annual service contracts available upon request
Power Supply: 110-220v/50-60Hz depending on the area of usage
Amino Acid Vessels:
Multiple Deliveries from 24x90mL Amino Acid/Reagent Vessels (Standard Option)
Direct dissolving and pre-activation of amino acid powders by the instrument
Pre-activation and deliveries under inert conditions
Optional 250mL and 500mL (or even larger) Amino Acid Vessels for Large Scale Syntheses (The Focus XCi model)
Use of pre-dissolved solutions of monomers, if required
Can be used as Cleavage Vessels, Reagent Bottles as well as Solution Phase Reactors for the synthesis of any desired intermediate of final compounds
Reaction Vessels:
Average Scales in 25-100mL Reactors: 0.01-5.0mmol per Reactor (Total 30mmol in 6RV model based 0.5mmol/g resin loading)
Ultimate Scale in 300mL Reactors: 15mmol per Reactor (Total 45mmol in 4-6RV model based 0.5mmol/g resin loading)
Easily interchangeable Reactors for multiple scale-up purposes.
Available Reactor Volumes: 25mL; 50mL, 100mL, 200mL, 300mL
Special Reactor system for larger scales (0.5-2L) maybe designed upon request (The Focus XCi model).
Solvent Delivery from the Top as well as Bottom of the Reactor under inert conditions
Fast Emptying of the Reaction Vessels by a positive pressure of an inert gas regulated at 10psi
Shower Head Technology For Fast and Cost Effective Washing of Resin and the entire reactors
Three Agitation modes at adjustable rates: Vortex Shaking, Nitrogen/Argon bubbling or the both
Optional Heating / Cooling / Microwave Systems upon request
Reagent/Solvent Vessels:
6-8 Flexible lines with interchangeable 0.5-20L containers for the Reagents and Solvents Deliveries
Standard Option: 2x5L; 2x2L; 2x1L containers
Measuring Vessel:
Interchangeable measuring vessels at different working volumes in 15-90mL (Optional larger or smaller measuring vessels available at extra charge)
Accurate calibration of all the liquid deliveries using Pressure/Time Calibration or photocell technology
Accurate measurements of liquids prior to deliveries
Pre-activation of amino acids (optional)
Software System:
Versatile Software installed on a desk top PC included with LCD-monitor, keyboard, mouse pad and a printer (Optional Laptop available upon request)
Unique and flexible capabilities developed by Chemists for Novice and Expert Chemists
User friendly Software for easy to prepare and easy to use
Fully Automated Optimized Standard Protocols for Fmoc- or BOC Peptide Chemistry
Flexible Custom Designable Protocols for ANY type of Solid Phase Organic Syntheses (PND, DNA, Oligopeptides, Carbohydrate Synthesis, etc)
Synthesis of Long Chain and/or Difficult Peptides at the shortest possible time: Pre-activation or In-Situ activation of the Amino Acids per need; Single or Multiple Couplings per need
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