BAMS M120 is a real-time airborne microbiological monitoring system, designed to meet the stringent standards in pharmaceutical manufacturing and controlled cleanroom environments. The device uses advanced optical sensor technology, combining Mie scattering and UV fluorescence methods to detect and classify biological particles in the air. BAMS M120 is capable of measuring particles ranging from 0.5µm to 25µm, with measurement channels at 0.5µm, 1.0µm, 2.0µm, 3.0µm, 5.0µm, and 10.0µm.
The system provides continuous data, requiring no sample culturing, enabling immediate detection of microbiological contamination and reducing the risk of product loss. The airflow rate is 2.83 LPM ±3%, ensuring high measurement accuracy. BAMS M120 integrates an 8.0-inch LCD touchscreen, supporting a user-friendly interface. The device can connect via RJ45, USB, WiFi, allowing remote monitoring and flexible data retrieval. Additionally, the system features an integrated audible alarm for timely contamination detection.
Constructed from 316L stainless steel, BAMS M120 ensures durability and stable operation in harsh conditions.
Real-time airborne microbiological monitoring: No sample culturing required, results are immediate. Supports pharmaceutical manufacturing quality control: Helps early detection of contamination, reducing the risk of product loss. Pollution trend analysis: Continuous data tracking helps identify the root causes of contamination. Applications in aseptic production lines: Ensures a clean environment for sterility testing. Modern optical sensor technology: Identifies particle sizes and detects the fluorescence of microorganisms.
Operating principle of Mie scattering and UV fluorescence methods:
Mie scattering is the phenomenon of light scattering when it encounters particles with sizes comparable to or larger than the wavelength of light. In BAMS M120, laser light is directed at particles in the air, and the degree of scattering helps determine the particle size.
UV fluorescence uses ultraviolet (UV) light to excite biological compounds like NADH and riboflavin in microorganisms. When these compounds are excited, they emit light, helping detect live biological particles in the air.
By combining these two methods, the device can accurately detect the presence and size of microorganisms in the environment.
Comparison between compendial methods and BAMS:
Result Time:
- Compendial method:
- Takes 1 to 7 days for results.
- Prone to interruptions due to scheduling or unforeseen events.
- Difficult to identify the cause of contamination.
- BAMS:
- Provides immediate results.
- Easily identifies the root cause of contamination.
Detection Frequency:
- Compendial method:
- Sample-based monitoring, not continuous.
- Lower accuracy.
- Limited in tracking pollution trends.
- Higher risk of contamination and product loss.
- BAMS:
- Continuous monitoring.
- Provides trend data and advanced analysis.
- Reduces the risk of contamination and production loss.
Coordination and Resources:
- Compendial method:
- Requires significant resources and manpower.
- Causes delays in testing processes.
- Higher labor costs.
- BAMS:
- Optimizes cost and resources.
- Provides immediate and online data.
BAMS offers more benefits compared to compendial method due to continuous monitoring, immediate results, reduced contamination risks, and optimized operational costs.
Technical Specifications of BAMS M120:
- Model: M120
- Touchscreen: 8-inch
- Continuous monitoring: 24/7
- Particle Size Range: 0.5µm – 25µm
- Laser Source: Long-lifetime laser
- Counting Performance:
- 50% ±20% for 0.5µm particles
- 100% ±10% for particles >0.75µm (compliant with ISO 21501-4 and JIS B9921 standards)
- Airflow Rate: 2.83 LPM ±3%
- Monitoring Area / Monitoring Points: 20,000 rooms and 200,000 locations
- Sampling Mode:
- Manual, automatic, audible alarm
- Accumulated counting (Σ), differential counting (Δ), or concentration measurement
- Concentration Limit: 4,000,000 particles/ft³ at 10% uniformity loss
- Exhaust Filter: Internal HEPA filter (>99.999% @ 0.3µm)
- Connectivity: RJ45, USB, SENSOR-HUB, WiFi (optional)
- Data Export Format: PDF or Excel
- Data Memory: 119GB
- Data Security: Role-based access control with levels for administrator, operator, and supervisor
- Alerts: Built-in alarm sound
- Dimensions (L x W x H): 255 x 200 x 264 mm (with handle and footpads)
- Weight:
- 6.8 kg (including battery)
- 5.8 kg (without battery)
- Enclosure: 316L stainless steel and anodized aluminum
- Operating Conditions:
- Temperature: 5°C – 35°C / 41°F – 95°F
- Relative Humidity: 5 – 90% (non-condensing)
- Storage Conditions:
- Temperature: 0°C – 40°C / 32°F – 104°F
- Relative Humidity: 5 – 95% (non-condensing)
- Safety Standards:
- EN 61010-1:2010+A1:2019
- EN 61326-1:2013, EN 61326-2-2:2013
- EN 60825-1:2014
- EN 61000-6-1:2007, EN 61000-6-3:2007+A1
- EN 62311:2008, EN 62479:2010
- Warranty: 12 months (from product activation date or 6 months after manufacturing date, whichever comes first)